JORONAC AQ Injection

Diclofenac 75 mg / 1 ml AQ Injection (Painless Formula)

JORONAC AQ Injection

Suitable As Initial Therapy For Inflammatory And Degenerative

Rheumatic Diseases As Well As For The Treatment Of Painful

Conditions Due To Inflammation Of Non-Rheumatic Origin

Composition:

Diclofenac 75 Mg / 1 Ml AQ Injection (Painless Formula)

INDICATION OF DICLOFENAC 75 MG INJECTION :

RHEUMATOID ARTHRITIS
OSTEOARTHRITIS
LOW BACK PAIN
ANKYLOSING SPONDYLITIS
GOUT
ACUTE MUSCULO SKELETAL DISORDERS
PERIARTHRITIS {FROZEN SHOULDER}
TENOSYNOVITIS
BURSITIS
DISLOCATIONS
PAINFUL POST OPERATIVE CONDITIONS
PAINFUL INFLAMMATORY CONDITIONS IN GYNAECOLOGY

CONTRA-INDICATIONS OF DICLOFENAC 75 MG INJECTION :

HYPERSENSITIVITY
ACTIVE PEPTIC ULCER
TREATMENT OF PERIOPERATIVE PAIN IN CABG SURGERY

DRUG INTERACTION OF DICLOFENAC 75 MG INJECTION :

INCREASE BLOOD LEVELS OF LITHIUM & DIGOXIN
INHIBITS DIURETICS
NOT TO BE GIVEN IV TO PATIENTS WHO ARE RECEIVING OTHER NSAIDS OR ANTICOAGULANTS INCLUDING LOW DOSE HEPARIN.
INCREASED RISK OF GI ULCERATION AND BLEEDING WHEN USED WITH CORTICOSTEROIDS, ASPIRIN OR ANTICOAGULANTS.
RENAL FUNCTION MAY BE WORSENED WHEN USED WITH CICLOSPORIN OR TRIAMTERENE.
ALTERED ABSORPTION WHEN GIVEN WITH SUCRALFATE, COLESTYRAMINE OR COLESTIPOL.

SIDE EFFECTS OF DICLOFENAC 75 MG INJECTION :

EPIGASTRIC PAIN
NAUSEA
DIARRHOEA
TIREDNESS
INSOMNIA
SKIN RASH
ITCHING
GI DISTURBANCES
HEADACHE
DIZZINESS
GI BLEEDING
PEPTIC ULCERATION
ABNORMALITIES OF KIDNEY FUNCTION
LOCAL IRRITATION (RECTAL)

MECHANISM OF ACTION OF DICLOFENAC 75MG:

DICLOFENAC HAS POTENT ANTI-INFLAMMATORY, ANALGESIC AND ANTIPYRETIC ACTIONS. IT INHIBITS THE ENZYME, CYCLOOXYGENASE, THUS RESULTING IN REDUCED SYNTHESIS OF PROSTAGLANDIN PRECURSORS. ABSORPTION: RAPIDLY ABSORBED (ORAL SOLUTION, RECTAL SUPPOSITORY, IM); MORE SLOWLY (ENTERIC-COATED TAB). DISTRIBUTION: PENETRATES SYNOVIAL FLUID; ENTERS BREAST MILK (SMALL AMOUNTS). PROTEIN-BINDING: >99%. METABOLISM: EXTENSIVELY HEPATIC; CONVERTED TO METABOLITES. EXCRETION: ABOUT 60% EXCRETED IN URINE AS GLUCURONIDE AND SULFATE CONJUGATES; 35% IN BILE; 1-2 HR (ELIMINATION HALF-LIFE).

SPECIAL PRECAUTIONS FOR DICLOFENAC 75MG:

HISTORY OF GI ULCERATION; IMPAIRED CARDIAC, RENAL OR HEPATIC FUNCTION; HYPERTENSION; LACTATION. IV ADMIN IN PATIENTS WITH MODERATE OR SEVERE RENAL IMPAIRMENT; HYPOVOLAEMIA OR DEHYDRATION; ASTHMA, PORPHYRIA. MONITOR LFTS IN PATIENTS ON PROLONGED THERAPY. MAY PROLONG BLEEDING TIME; CAUTION WHEN USED IN PATIENTS WITH COAGULATION DISORDERS OR ON ANTICOAGULANTS. PROLONGED THERAPY MAY INCREASE RISK OF ANAEMIA. 1ST AND 2ND TRIMESTER OF PREGNANCY. ELDERLY, DEBILITATED PATIENTS.

PACKAGING:

1 ML AQ INJECTION (PAINLESS FORMULA) BLISTER PACK BOX WITH 10*5 INJECTION.

For Use of Registered Medical Practitioner or a Hospital Only.