Permethrin 5 % Lotion Use, Indication, Side Effects, Dosage, Mechanism of Action, Price, Contra-Indications, Drug Interactions....

WEEVA Lotion (Permethrin 5% W/V)

Permethrin lotion is a medication primarily used to treat scabies and lice infestations in humans.

Indications:

• Scabies: A skin infestation caused by the Sarcoptes scabiei mite, leading to intense itching and a pimple-like skin rash.

• Lice Infestations: Effective against head lice and pubic lice (crab lice).

Mechanism of Action:

• Permethrin, a synthetic pyrethroid, disrupts the sodium channel current in nerve cell membranes of insects and mites. This disruption leads to paralysis and death of the parasites, effectively eliminating the infestation.

Dosage:

• Scabies:

  • Apply the lotion thoroughly over the entire body from the neck down.

  • Leave it on for 8–14 hours before washing off.

  • A second application may be necessary after 7 days.

• Head Lice:

  • Apply to the scalp, ensuring all hair is covered.

  • Leave on for 10 minutes, then rinse off with water.

• Pubic Lice:

  • Apply to affected areas, leave on for 10 minutes, then rinse off.

Side Effects:

• Common Side Effects:

  • Skin irritation such as itching, redness, swelling.

  • Tingling or numbness of the skin.

  • Mild burning or stinging sensations.

• Less Common but Severe Side Effects:

  • Allergic reactions like rash, hives, difficulty breathing.

  • Severe skin irritation.

  • Eye irritation if the lotion comes into contact with eyes.

• Note: If any of these side effects occur, discontinue use and consult a healthcare professional promptly. 

Contraindications:

• Hypersensitivity: Contraindicated in individuals allergic to Permethrin, other pyrethroids, or pyrethrins.

• Children: Not recommended for use in children under 2 months of age.

• Pregnancy and Breastfeeding: Use during pregnancy and breastfeeding should be under medical supervision, as limited data is available. 

Drug Interactions:

• Corticosteroids: Concurrent use with corticosteroids may exacerbate scabies infestations. It's advisable to discontinue corticosteroids before starting Permethrin treatment.

• Other Topical Treatments: Use caution when combining with other topical products to avoid skin irritation.

• Inform Healthcare Provider: Always disclose all current medications, including over-the-counter drugs and supplements, to your healthcare provider before starting Permethrin lotion.

For Use of Registered Medical Practitioner or A Hospital Only

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